Dual block following tacrine and suxamethonium.

Tacrine and suxamethonium were used to produce muscle relaxation in 29 anaesthetized patients. Relaxation was monitored with a nerve stimulator. Post-tetanic facilitation was observed in 24 patients (83 per cent). In spite of this, operating conditions were satisfactory in 26 patients. Poor operating conditions were associated with the more severe degrees of phase II block as judged by an increasingly obvious post-tetanic facilitation. The value of the nerve stimulator and the indications for further doses of tacrine or for changing to an anti-depolarizing relaxant are discussed.